Dr. April Brown was born and raised in Hope, Arkansas. In 2001, she graduated from Hope High School as valedictorian of her class. She attended Ouachita Baptist University and earned her Bachelor of Science degree with Summa Cum Laude status. In 2004, she attended the University of Louisville School of Dentistry in Kentucky and received her Doctorate of Dental Medicine and also completed her Masters in Oral Biology at the same time.
While in dental school, Dr. Brown was involved in the Louisville American Student Dental Association, the Christian Medical/Dental Association, and the Alpha Omega dental fraternity. She was appointed to a position on the Dental School Admissions Committee and was the Colgate liaison for the entire school in her junior and senior years.